Skin Renewal
Tretinoin promotes epidermal cell turnover and influences collagen-remodeling pathways.
$199.00
A prescription nighttime cream combining estriol, tretinoin, antioxidants, and hydration support to improve skin texture, tone, firmness, and visible signs of aging.
Supports smoother, more even-looking skin: Tretinoin promotes skin-cell turnover and renewal to improve texture and tone.
Supports collagen & firmness: Tretinoin, vitamin C, and estrogen-responsive pathways support processes involved in collagen and skin structure.
Boosts hydration: Hyaluronic acid attracts and retains moisture to support smoother, more hydrated skin.
Provides antioxidant support: Vitamin C and alpha lipoic acid help support the skin’s defenses against oxidative stress.
Avoid use during pregnancy. Patients who are pregnant, may be pregnant, or are planning pregnancy should notify their prescribing clinician before using this product.
Because DB Night Cream Lite contains an estrogen component, discuss your medical history with your clinician, particularly if you have a history of or risk factors for:
Daily sunscreen is recommended while using this product.
Avoid applying to significantly irritated, broken, sunburned, or eczematous skin unless otherwise instructed. Other retinoids, exfoliating acids, scrubs, or irritating acne treatments may increase skin irritation.
Potential side effects may include:
Irritation may be more noticeable when treatment is first started.
Tretinoin is a prescription retinoid that supports skin-cell turnover and collagen-remodeling pathways. With continued use, it may improve skin texture, uneven pigmentation, fine lines, and signs of photodamage.
Estriol is an estrogen that interacts with estrogen receptors. Estrogen signaling in the skin is involved in processes affecting collagen, hydration, elasticity, and extracellular matrix function, which has led to research into topical estrogen for age-related skin changes. Estriol-containing drugs are not FDA-approved.
Hyaluronic acid attracts and retains water, helping support skin hydration, smoothness, moisture retention, and the appearance of fullness.
Vitamin C and alpha lipoic acid provide antioxidant support. Vitamin C also serves as an important cofactor in normal collagen synthesis, while alpha lipoic acid participates in cellular redox pathways.
Yes. Use sunscreen during the daytime. Sun protection is particularly important while using tretinoin as part of a nighttime skincare regimen.
DB Night Cream Lite already contains 0.025% tretinoin. Adding another retinoid or other strongly irritating topical products may increase dryness, redness, peeling, and irritation. Review your other skincare products with your clinician.
No. DB Night Cream Lite is a compounded prescription formulation and is not FDA-approved as a combination drug. Compounded medications are not reviewed by FDA for safety, effectiveness, or quality before marketing.
DB Night Cream Lite is a compounded prescription nighttime cream combining 0.3% estriol, 0.025% tretinoin, alpha lipoic acid, vitamin C, and hyaluronic acid.
The formulation combines ingredients that target complementary pathways involved in skin-cell renewal, collagen biology, antioxidant defense, hydration, texture, and elasticity.
Its lower-strength tretinoin concentration is designed to provide provider-guided nighttime skin renewal while supporting tolerability.
DB Night Cream Lite is a compounded formulation and is not FDA-approved as a combination product.
All dosing should follow the instructions provided by the prescribing clinician.
DB Night Cream Lite combines five ingredients that target complementary aspects of skin renewal and appearance.
Tretinoin promotes epidermal cell turnover and influences collagen-remodeling pathways.
Estriol interacts with estrogen receptors involved in skin physiology, including pathways related to collagen, hydration, elasticity, and extracellular matrix function.
Vitamin C and alpha lipoic acid provide antioxidant support, while vitamin C also contributes to normal collagen synthesis.
Hyaluronic acid attracts and retains moisture to support hydration, smoothness, and skin-barrier function.
Tretinoin is an established prescription retinoid used in FDA-approved topical products for certain dermatologic indications. However, DB Night Cream Lite as a compounded combination is not FDA-approved, and estriol-containing compounded products have not undergone FDA premarket review for safety or effectiveness.
All dosing should follow the instructions provided by the prescribing clinician.
DB Night Cream Lite combines five active ingredients that target complementary pathways potentially involved in skin renewal, collagen maintenance, antioxidant defense, and hydration. Tretinoin may support epidermal cell turnover and collagen remodeling, while estriol interacts with estrogen receptors that may influence pathways related to collagen, elasticity, hydration, and extracellular matrix function. Vitamin C and alpha lipoic acid provide antioxidant activity, while vitamin C serves as a cofactor for collagen synthesis and hyaluronic acid may support hydration, smoothness, and skin-barrier function through its ability to attract and retain water.
