
Three Ingredients
Combines three active ingredients that target different aspects of under-eye skin appearance, including puffiness, fine lines, texture, and tone.
$199.00
A prescription eye cream combining caffeine, tretinoin, and glycolic acid to target puffiness, fine lines, uneven texture, and dull-looking under-eye skin.
Avoid direct contact with the eyes. DB Eye Cream is intended for the skin surrounding the eye area and should not be applied directly to the eye, inner eyelid, or other mucosal surfaces.
Use sunscreen daily. Tretinoin and glycolic acid can increase skin sensitivity and irritation associated with environmental exposure.
Because this formulation contains both tretinoin and glycolic acid, additional irritating skincare products may increase redness, dryness, peeling, and sensitivity. Review your routine with your clinician if you use:
Avoid applying to significantly irritated, broken, sunburned, or eczematous skin unless otherwise directed.
Pregnancy: Because this formulation contains topical tretinoin, patients who are pregnant, may be pregnant, or are planning pregnancy should discuss use with their prescribing clinician before treatment.
Potential side effects may include:
The skin around the eyes is particularly delicate, so individual tolerability can vary.
Topical caffeine can influence vascular tone and has antioxidant properties. It may temporarily improve the appearance of puffiness and certain types of under-eye discoloration.
Tretinoin promotes skin-cell turnover and collagen-remodeling pathways. With continued use, these effects may help improve the appearance of fine lines, texture, and other visible signs of photoaging.
Glycolic acid is an alpha hydroxy acid (AHA) that promotes exfoliation of the skin’s outer layers. This may help improve the appearance of roughness, dullness, uneven texture, and superficial pigmentation.
It may improve the appearance of certain types of under-eye discoloration through caffeine’s vascular effects and glycolic acid’s exfoliating activity. However, dark circles can have many causes—including pigmentation, visible blood vessels, thin skin, genetics, and facial anatomy—so a topical cream will not address every cause.
Tretinoin may be incorporated into provider-guided periorbital skincare protocols, but the skin surrounding the eyes is particularly sensitive. Apply only as directed and avoid direct contact with the eyes and mucosal surfaces.
Follow the exact application instructions provided with your prescription.
Yes. Daily sunscreen is recommended. Sun protection is particularly important when using topical tretinoin and exfoliating acids.
No. DB Eye Cream is a compounded prescription formulation and is not FDA-approved as a combination drug. This specific compounded combination has not undergone FDA premarket review for safety and effectiveness.
DB Eye Cream is a compounded prescription topical formulation combining 1% caffeine, 0.025% tretinoin, and 2.5% glycolic acid.
The formulation combines three ingredients with complementary effects on puffiness, skin-cell renewal, collagen remodeling, exfoliation, texture, and uneven tone to target multiple visible concerns around the delicate under-eye area.
DB Eye Cream is a compounded formulation and is not FDA-approved as a combination drug.
All dosing should follow the instructions provided by the prescribing clinician.

Combines three active ingredients that target different aspects of under-eye skin appearance, including puffiness, fine lines, texture, and tone.

Uses caffeine to influence blood vessel activity, which may temporarily reduce the appearance of under-eye puffiness.

Incorporates tretinoin to promote skin-cell turnover and support collagen remodeling, helping improve skin texture and the appearance of fine lines.

Includes glycolic acid to exfoliate the skin’s surface, helping improve dullness, uneven texture, and superficial discoloration.
Tretinoin is an established prescription retinoid used in FDA-approved topical products for certain dermatologic indications. However, DB Eye Cream itself is a compounded combination formulation and is not FDA-approved.
All dosing should follow the instructions provided by the prescribing clinician.
DB Eye Cream combines caffeine, tretinoin, and glycolic acid to target complementary pathways that may influence under-eye appearance, skin renewal, and texture. Caffeine has vasoconstrictive and antioxidant properties that may help reduce the appearance of puffiness, while tretinoin may support epidermal cell turnover and influence collagen-remodeling pathways. Glycolic acid promotes exfoliation and may support cellular renewal, potentially improving the appearance of skin texture, smoothness, and uneven tone.
