Redox Coenzyme
NAD+ functions as an essential redox coenzyme, cycling between NAD+ and NADH as cells process nutrients.
$299.00
A convenient, non-injectable NAD+ troche designed to support cellular energy metabolism, mitochondrial function, and healthy cellular processes.
Supports cellular energy metabolism: NAD+ is an essential coenzyme involved in pathways that convert nutrients into usable cellular energy.
Supports mitochondrial function: NAD+/NADH cycling plays a central role in mitochondrial ATP production.
Supports cellular maintenance & redox balance: NAD+ participates in cellular signaling, maintenance pathways, and essential oxidation-reduction reactions.
Convenient non-injectable delivery: A once-daily troche provides an alternative option for clinician-directed NAD+ supplementation.
Oral sensitivity: Because the troche dissolves between the cheek and gum, some individuals may experience temporary irritation or sensitivity of the gums, cheek, tongue, or oral tissues. Persistent irritation should be reported to your clinician or dispensing pharmacy.
Other NAD+ products: Tell your clinician if you use other NAD+-related products, including injectable NAD+, NR, NMN, niacinamide, or niacin. These products are not interchangeable and can differ in metabolism, dosing, absorption, and clinical evidence.
Pregnancy & breastfeeding: Clinical safety data for supplemental compounded NAD+ during pregnancy and breastfeeding are limited. Patients who are pregnant, planning pregnancy, or breastfeeding should discuss use with their clinician.
Persistent symptoms: Fatigue, difficulty concentrating, and cognitive changes can have many underlying causes and should not automatically be attributed to NAD+ status. Persistent or unexplained symptoms may require medical evaluation.
Potential side effects may include:
Individual response and tolerability may vary.
NAD+ is a naturally occurring coenzyme involved in cellular energy metabolism, mitochondrial function, redox reactions, cellular signaling, and metabolic regulation. It participates in hundreds of biochemical reactions throughout the body.
Yes. NAD+ is essential for biochemical pathways that help cells convert nutrients into usable energy. However, NAD+ is not a stimulant and does not directly provide energy in the way calories or ATP do.
Yes. NAD+/NADH cycling is fundamental to mitochondrial metabolism. NADH transfers electrons into the mitochondrial electron transport chain, contributing to the process used to produce ATP.
NAD+ is essential for neuronal energy metabolism, and NAD-related pathways are being studied in relation to brain and cognitive health. However, clinical evidence that oral NAD+ reliably improves focus in otherwise healthy individuals remains limited.
No. NAD+ metabolism is actively studied in aging biology because of its relationship with mitochondrial function, sirtuins, metabolic regulation, and cellular stress responses. However, supplemental NAD+ has not been proven to reverse aging or extend human lifespan.
Both formulations contain NAD+, but their routes of administration, absorption, pharmacokinetics, dosing, and formulation characteristics differ. The oral/buccal troche should not be assumed to provide the same systemic exposure or clinical effects as injectable NAD+.
The supplied instructions direct the troche to be placed between the cheek and gum and allowed to dissolve. This is known as buccal administration. Follow the exact instructions provided with your prescription.
No. This compounded NAD+ Oral Troche formulation is not FDA-approved. Its use for energy, focus, metabolic health, cognitive support, or healthy-aging purposes has not undergone FDA premarket review for these indications.
NAD+ Oral Troche is a compounded 250 mg nicotinamide adenine dinucleotide (NAD+) formulation designed to dissolve between the cheek and gum.
NAD+ is a naturally occurring coenzyme essential for cellular energy metabolism, mitochondrial function, redox reactions, metabolic signaling, and cellular maintenance pathways.
The troche provides a convenient non-injectable option for clinician-directed NAD+ supplementation.
This compounded NAD+ Oral Troche formulation is not FDA-approved.
All dosing should follow the instructions provided by the prescribing clinician.
NAD+ functions as an essential redox coenzyme, cycling between NAD+ and NADH as cells process nutrients.
NADH transfers electrons into the mitochondrial electron transport chain, supporting the process used to produce ATP—the primary energy currency of cells.
NAD+ also serves as a substrate for enzymes including sirtuins and PARPs, connecting NAD+ metabolism with cellular signaling, stress responses, metabolic regulation, and DNA-related maintenance pathways.
These mechanisms explain the scientific interest in NAD+ for cellular energy and healthy-aging research, but clinical evidence for compounded oral NAD+ remains developing.
These uses are investigational and should be distinguished from FDA-approved indications. NAD+ Oral Troche is not FDA-approved to treat fatigue, cognitive impairment, mitochondrial disease, age-related conditions, or to extend lifespan.
All dosing should follow the instructions provided by the prescribing clinician.
NAD+ Troche contains nicotinamide adenine dinucleotide (NAD+), an essential cellular coenzyme involved in redox reactions that help convert nutrients into usable energy within the mitochondria. NAD+ also serves as a substrate for enzymes including sirtuins and PARPs, which participate in metabolic signaling, cellular stress responses, DNA repair, and mitochondrial function. Because NAD+ availability is closely linked to cellular energy metabolism and may decline with age and metabolic stress, NAD+ pathways are an active area of research in cellular resilience, mitochondrial health, and healthy aging.
