Oxytocin
Is a naturally occurring neuropeptide involved in social bonding, emotional processing, attachment, and aspects of sexual response.
$299.00
An on-demand prescription tablet combining tadalafil, sildenafil, and oxytocin to support erectile response, blood flow, and sexual wellness.
Supports erectile function: Tadalafil and sildenafil enhance nitric oxide-cGMP signaling involved in the body’s natural erectile response.
Enhances penile blood flow: PDE5 inhibition supports smooth-muscle relaxation and increased blood flow during sexual stimulation.
Supports erectile rigidity & maintenance: Increased cGMP signaling can help support the ability to achieve and maintain an erection.
Multi-pathway sexual wellness support: Combines vascular erectile support with oxytocin-related neuroendocrine signaling in one formulation.
Nitrates — contraindicated: Do not use this medication with nitrate medications such as nitroglycerin, isosorbide mononitrate, or isosorbide dinitrate. The combination can cause a dangerous and potentially life-threatening drop in blood pressure.
Riociguat: PDE5 inhibitors should not be combined with riociguat because of the risk of clinically significant hypotension.
Blood pressure & cardiovascular health: Both tadalafil and sildenafil can lower blood pressure. Additional caution may be needed with low baseline blood pressure, cardiovascular disease, fainting, certain heart conditions, blood-pressure medications, alpha-blockers, or significant dehydration.
Other ED medications: This product already contains two PDE5 inhibitors. Do not independently add tadalafil, sildenafil, vardenafil, avanafil, or other compounded ED medications unless specifically directed by your clinician.
Priapism: An erection lasting more than 4 hours requires urgent medical attention to reduce the risk of permanent tissue injury.
Vision & hearing changes: Sudden vision loss, a significant sudden change in vision, or sudden hearing decrease/loss requires prompt medical evaluation.
Oxytocin: Patients with significant psychiatric, mood, cardiovascular, or other relevant medical conditions should discuss their history with their prescribing clinician.
Potential side effects may include:
Individual response and tolerability may vary.
Tadalafil and sildenafil both inhibit PDE5, enhancing nitric oxide-mediated cGMP signaling. This helps relax smooth muscle and increase blood flow to erectile tissue during sexual stimulation.
Both medications act on the PDE5 pathway but have different pharmacokinetic profiles. A clinician may prescribe the combination as part of an individualized sexual-health protocol. Because combining PDE5 inhibitors can also increase the potential for side effects, it should be used only as prescribed.
No. Tadalafil and sildenafil enhance the body’s natural erectile response, but sexual stimulation is still required to initiate the nitric oxide-cGMP pathway involved in an erection.
Oxytocin is a naturally occurring hormone and neuropeptide involved in social bonding, attachment, emotional processing, reproductive physiology, and aspects of sexual response. Its effects on sexual function can vary considerably between individuals.
No. This medication is contraindicated with nitrates. Combining nitrate medications with tadalafil or sildenafil can cause a dangerous and potentially life-threatening drop in blood pressure.
Do not independently combine this formulation with other PDE5 inhibitors or erectile-dysfunction medications. It already contains both tadalafil and sildenafil. Any additional ED medication should be discussed with your prescribing clinician.
Always follow the exact directions provided with your prescription.
No. This compounded Tadalafil / Sildenafil / Oxytocin Triturate is not FDA-approved as a combination drug. Although tadalafil and sildenafil have individually approved indications and oxytocin has approved uses in other formulations, this specific compounded combination has not undergone FDA premarket review for safety or effectiveness.
Tadalafil / Sildenafil / Oxytocin Triturate is a compounded prescription tablet containing Tadalafil 10 mg, Sildenafil 20 mg, and Oxytocin 250 units.
Tadalafil and sildenafil are PDE5 inhibitors that support erectile response and penile blood flow during sexual stimulation. Oxytocin is a naturally occurring neuropeptide involved in social, emotional, reproductive, and sexual-response pathways.
Together, the formulation provides a multi-pathway approach to sexual wellness by combining vascular erectile support with neuroendocrine signaling.
This compounded combination is not FDA-approved as a combination drug.
Is a naturally occurring neuropeptide involved in social bonding, emotional processing, attachment, and aspects of sexual response.
Inhibit PDE5, helping preserve cGMP signaling within erectile tissue. This promotes smooth-muscle relaxation and increased penile blood flow, supporting the body’s natural erectile response.
The two medications have different pharmacokinetic profiles, with tadalafil providing a relatively longer duration of pharmacologic activity.
This formulation combines vascular erectile physiology with neuroendocrine pathways associated with sexual experience and connection.
When clinically appropriate, this formulation may be prescribed as part of an individualized sexual-health protocol focused on:
Persistent erectile dysfunction can have multiple underlying causes—including cardiovascular or vascular disease, diabetes, hormonal changes, neurological conditions, medications, psychological factors, and stress—and may warrant additional medical evaluation.
Tadalafil / Sildenafil / Oxytocin Triturate combines two PDE5 inhibitors, tadalafil and sildenafil, with the neuropeptide oxytocin to target complementary vascular and neuroendocrine pathways involved in sexual response. Tadalafil and sildenafil inhibit phosphodiesterase type 5 (PDE5), helping preserve nitric oxide–cGMP signaling involved in smooth-muscle relaxation and genital blood flow, while oxytocin interacts with receptors in the brain and peripheral tissues associated with arousal, intimacy, and sexual behavior. Through these distinct mechanisms, the combination may support multiple physiological pathways involved in sexual function and response.
